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2025 MLB All-Star Game betting preview (July 15)
National League pitcher Paul Skenes of the Pittsburgh Pirates (30) pitches against the American League in the first inning during the 2024 MLB All-Star game at Globe Life Field
Photo credit: Kevin Jairaj-Imagn Images
Greg Warren
Jul 15, 2025, 15:42 EDTUpdated: Jul 15, 2025, 20:48 EDT
MLB All-Star week is the perfect time for bettors to take a break and let their sports betting apps cool off a bit, but if you can’t get enough baseball action, the 95th MLB All-Star Game is set to take place Tuesday in Atlanta.
The American League has dominated the event in recent history, taking 10 of the last 11 All-Star Games. The National League eked out a 3-2 victory in 2023 at T-Mobile Park in Seattle to snatch its lone victory in the last decade or so.
Let’s take a look at the game odds for the 95th MLB All-Star Game courtesy of bet365.
American League moneyline odds
-105
National League moneyline odds
-115
Runline odds
NL -1.5 (+185), AL +1.5 (-225)
Game total
Over 7 runs (-120), Under 7 (+100)
Date/time
July 15, 8 p.m. ET

American League lineup

Toronto Blue Jays slugger Vladimir Guerrero Jr. will start at first base and bat fifth for the American League. He’ll be joined on the AL roster by Blue Jays teammate Alejandro Kirk, who will serve as a reserve catcher for the squad.
Home Run Derby champion Cal Raleigh will start at catcher and bat cleanup for a solid AL starting lineup.

National League lineup

The National League will roll out a very impressive starting lineup with several familiar faces to the Midsummer Classic, including Shohei Ohtani, who will bat leadoff while serving as the designated hitter.
In the midst of a breakout season, Pete Crow-Armstrong will appear in his first career All-Star game as a starter at centre field. He’ll be joined by Cubs teammate Kyle Tucker, who will start alongside Crow-Armstrong in right field.

Probable starting pitchers

AL: LHP Tarik Skubal (10-3, 2.23 ERA, 11.38 K/9)
Skubal, the reigning AL Cy Young Award winner, will be making his first All-Star start for the AL. He amazingly ranks in the 94th percentile in chase rate, 94th percentile in whiff rate, 95th percentile in strikeout rate, and 99th percentile in walk rate. Historically, starting pitchers in All-Star Games never pitch more than two innings (usually only one), and he should match up well against some of the left-handed batters in the NL starting lineup, including Ohtani, Freeman, and potentially Tucker.
NL: RHP Paul Skenes (4-8, 2.01 ERA, 9.74 K/9)
Skenes will be making his second consecutive start in the Midsummer Classic for the NL. He threw one scoreless inning in the 2024 All-Star game without recording a strikeout. Skenes, the 2024 Rookie of the Year, is 4-8 this season but enters the contest with a league-best 2.01 ERA along with 131 strikeouts in 131 innings.

Weather

Forecasts are calling for temperatures around 28 C with a 40% chance of showers. Winds will be light out of the south and won’t be a factor.

MLB All-Star Game betting trends

  • The AL has gone 28-7-1 SU in the All-Star Game since 1988.
  • Unders are 13-5 in the All-Star Game since 2005.
  • A batter has won eight of the last 11 ASG MVPs.

MLB All-Star Game MVP odds

Player
MVP Odds
Shohei Ohtani
+500
Aaron Judge
+600
Ronald Acuna Jr.
+1000
Cal Raleigh
+1100
Pete Crow-Armstrong
+1100
Bobby Witt Jr.
+1800
Kyle Tucker
+2000
Vladimir Guerrero Jr.
+2200
James Wood
+2500
Ketel Marte
+2500
The last two All-Star Game MVPs —Jarren Duran and Elias Diaz—were huge longshots to haul in MVP honors, so it’s incredible difficult to project the winner of this award in such a star-studded affair. I wouldn’t recommend betting into this wildly unpredictable market, but if you decide to throw down a wager, why not back your favorite player purely from a rooting interest perspective?

MLB All-Star Game predictions

  • The All-Star Game is wildly unpredictable with the expanded rosters and the constant lineup changes throughout the game. I would recommend staying away from all player props in this contest, as there’s no way to project how long any given player will see the field or how many at-bats they’ll get. The same goes for pitchers. Some will get a full inning of work, while others may only pitch to a batter or two, or not even make their way into the game. In fact, this is a great game to just enjoy purely from a viewing perspective without rooting on a wager, as it’s incredibly difficult to find betting angles with so many additional factors to consider compared to a traditional baseball game. If I was forced to make a bet, I would side with history and take the American League on the moneyline while also backing the under on the game total. As always, shop around for the best prices on these markets at online sportsbooks.

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