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MLB betting preview (June 10): Blue Jays vs. Cardinals predictions

Toronto Blue Jays catcher Alejandro Kirk (30) hits a solo home run against the St. Louis Cardinals during the eighth inning at Busch Stadium.

Photo credit: Jeff Curry-Imagn Images

By Greg Warren

Jun 10, 2025, 12:35 EDTUpdated: Jun 10, 2025, 18:48 EDT

The Toronto Blue Jays will continue their series in St. Louis on Tuesday night after they prevailed 5-4 in extra innings over the Cardinals in the series opener on Monday.

Toronto took a cozy 3-0 lead into the bottom of the eighth inning, but the Cardinals exploded for four runs to take the lead. The Blue Jays clawed their way back in the ninth inning to force extras, setting the stage for Alejandro Kirk’s go-ahead RBI double in the 10th that proved to be the difference in the game.

The Blue Jays have now won 11 of their last 14 games overall to move six games over .500.

Let’s take a look at the game odds for Tuesday’s clash between the Blue Jays and Cardinals, courtesy of bet365.

Blue Jays vs. Cardinals odds

Blue Jays moneyline odds	-115
Cardinals moneyline odds	-105
Runline odds	Blue Jays -1.5 (+145), Cardinals +1.5 (-170)
Game total	Over 8.5 runs (+100), Under 8.5 runs (-120)
Date/time	June 10, 7:45 p.m. ET

About the Blue Jays (36-30 SU, 40-26 ATS, 35-30-1 o/u)

Kirk homered and had four hits on Monday to power the Blue Jays to victory. The catcher is slashing a robust .370/.435/.521 with 16 RBIs over the last 30 days and boasts a 1.127 OPS in June.

The Blue Jays combined for 13 hits on the day and went 3-for-9 with runners in scoring position while stranding 10 total runners. They’ve been fairly productive with runners in scoring position this season, boasting a .271/.340/.407 slash line with a .747 OPS in those instances to rank around the middle of the pack in the majors.

The Blue Jays are now just four games back of the New York Yankees for the AL East lead and are sitting in the second AL wild-card spot heading into action Tuesday.

About the Cardinals (36-30 SU, 35-31 ATS, 36-28-2 o/u)

After being stifled by Jose Berrios for 6 2/3 innings, the Cardinals teed off on relievers Brendon Little and Yariel Rodriguez to mount what looked like an impressive comeback victory. But closer Ryan Helsley blew his third consecutive save after successfully converting his previous nine opportunities. He’s now blown five saves this season, which is one more than his entire 2024 total. You have to wonder, at least in the short term, if Phil Maton and/or Kyle Leahy will be given some save opportunities while Helsley figures things out.

A quick note for in-game bettors: the Cardinals are just 1-5 in extra-innings games this year. Only the lowly Colorado Rockies have been worse in those scenarios with a 0-4 mark.

Probable starting pitchers

Toronto: RHP Chris Bassitt (6-3, 3.56 ERA, 9.20 K/9)

Bassitt is a major reason why the Blue Jays have been so competitive this season. After two ugly starts against the Athletics and Rays, he rebounded with seven innings of one-run ball against the Phillies the last time he took the hill for his sixth win of the campaign. Bassitt has done a great job of mixing up and locating his eight pitches, but he has struggled on the road a little bit, posting a 1-3 record with a 4.86 ERA in six starts this season. At home, he’s 5-0 with a 2.48 ERA across seven starts.

St. Louis: RHP Miles Mikolas (4-2, 3.96 ERA, 5.28 K/9)

Bettors can expect Toronto to put a lot of balls in play against Mikolas, who ranks in the bottom two percent of pitchers in strikeout rate (13.8%). However, he’s been very good recently, posting a 3-0 record with a 3.08 ERA across five May starts before coughing up three runs over six innings to the Royals in his lone June start. Left-handed batters hit him well, producing a .276/.326/.396 slash line with three homers against the righty. Mikolas also has interesting day/night splits. He’s 2-1 with a 2.28 ERA while holding the opposition to a .231 batting average in five-day starts, but he’s struggled at night, posting a 5.35 ERA with opponents hitting .274 against him across seven games.

Notable injuries

Pitchers Ryan Burr (shoulder), Nick Sandlin (lat), Yimi Garcia (shoulder), and Max Scherzer (thumb) are all on the injured list for the Blue Jays. Outfielder Anthony Santander (shoulder) and outfielder Daulton Varsho (hamstring) are also on the shelf.

Outfielder Jordan Walker (wrist) is the only notable player currently on the IL for the Cardinals.

Weather

Forecasts are calling for temperatures around 22 C and clear skies this evening in St. Louis. Winds will blow from left field to right field at just 5 mph.

Blue Jays vs. Cardinals betting trends

The Blue Jays are 4-0 in their past four meetings with the Cardinals.
The over is 10-1 in Toronto’s last 11 games.
The over is 9-3 in the Cardinals’ last 12 games.
Toronto is the best team in the majors on the runline this season (40-26 ATS).
The Cardinals are 22-12 SU at home this season.

Blue Jays vs. Cardinals player prop trends

Bassitt has recorded five strikeouts or more in 10 of his 13 starts this season and is -103 to hit that mark against the Cardinals, who only strike out an average of 7.77 times per game.
Brendan Donovan has hit safely in five straight games and seven of his last 10. He’s -255 to get a hit.
George Springer has eclipsed 1.5 total bases in five straight games and is +110 to extend that streak.
Kirk has driven in at least one run in five straight games and is +170 to record at least one RBI in this contest.
It’s an extremely small sample size, but Nolan Gorman is 2-for-2 with two homers in his career against Bassitt. Odds aren’t yet posted for him to homer in this game.

Blue Jays vs. Cardinals best bets

Springer over 1.5 total bases: +120 for one unit (best odds @ Pinnacle). Springer has beaten this line in five straight games and at a 45% clip this season, so we’re getting fair value here at +120 odds (45.5% implied odds). Additionally, Springer is 5-for-9 with a home run in his career against Mikolas. Over the last 15 days, nine of Springer’s 12 hits have been for extra bases, and he boasts a 1.093 OPS in that span.
Kirk over 0.5 RBI: +170 for one unit (best odds @ FanDuel). Most online sportsbooks have adjusted their player props to account for Kirk’s wicked run at the plate, but there still appears to be value in backing him to drive in a run at +170. He’s achieved this mark in five straight games, eight of his last 10, and in 40% of his games played this season. Kirk ranks in the 98th percentile in hard-hit rate (57%) and the 97th percentile in strikeout rate (just 10.1%), so the advanced metrics suggest he’s a good bet to always put the ball in play for a chance to drive in a run. He’s also had some previous success against Mikolas, going 2-for-5 with a pair of RBIs.