Three players from the Los Angeles Angels won’t be making the trip to Toronto ahead of a three-game set.

Prior to Friday’s opener, the team placed relievers Aaron Loup, Ryan Tepera and outfielder Taylor Ward on MLB’s restricted list due to their vaccination statuses.

As a reminder, if an unvaccinated player crosses the Canadian/American border they’re immediately subject to a 14-day quarantine. That rule also applies to the Toronto Blue Jays players.

Loup, 34, was selected by the Blue Jays in the ninth round of the 2009 Draft and played seven big-league seasons from 2012-18. The left-hander logged 318.2 career innings, posting a 3.47 ERA, 3.49 FIP, 52 holds and six saves.

After spending last season with the New York Mets, where he registered a career-best 0.95 ERA, Loup signed a two-year, $17-million contract with the Angels over the off-season. He owns a 4.05 ERA and a 4.35 FIP across 46.2 innings in 51 appearances this season.

Tepera, 34, was also drafted by Toronto in 2009, chosen out of the 19th round. The right-hander made 216 career major-league appearances, producing a 3.64 ERA and a 4.41 FIP over 215.1 innings. He also converted 10 saves and 38 holds.

The 6-foot-1 hurler signed a two-year, $14-million contract with Los Angeles last winter. This season, he carries a 3.80 ERA and a 4.15 FIP through 45.0 innings in 46 appearances.

Ward, 28, is hitting .261/.351/.447 with 17 home runs and 46 RBIs across 427 plate appearances this season. He’s also recorded a career-best 128 wRC+ score.

In corresponding moves, the Angels have recalled right-handers José Marte, Gerardo Reyes and outfielder Ryan Aguilar.