The Toronto Blue Jays take a good track record in interleague play into their first home series of the season at Sahlen Field in Buffalo. The Blue Jays are -150 home favorites and the Miami Marlins are +130 underdogs with an 8.5-run total on the MLB odds for Tuesday at sportsbooks monitored by OddsShark.com (how the moneyline works).

The Blue Jays are 10-4 in their last 14 home games against NL East teams, with the OVER hitting nine times at online sports betting sites. The Marlins are 8-12 in their last 20 away games against AL East teams, with the OVER hitting 13 times. Moneyline-wise, the Blue Jays are 9-11 in their last 20 home games as a -145 to -175 favorite, with the total going OVER 12 times. The Marlins are 6-14 in their last 20 away games as +125 to +155 underdogs, with the total going UNDER the last four times the moneyline closed in that range.

The Marlins, who are 24-28, are averaging 3.87 runs per game, which ranks 23rd out of the 30 MLB teams. Their .664 OPS (on-base plus slugging percentages) ranks 26th. Miami’s pitching staff has the eighth-best ERA (3.40), and their relievers are sixth (3.54) in bullpen ERA.

The Blue Jays, who are 27-25, have MLB’s fourth-best offense at 5.02 runs per game, with the second-best OPS at .764. Toronto’s pitching staff has the 12th-best ERA (3.91), while their relievers rank ninth (3.56).

Lefthander Robbie Ray (2-2, 3.81 ERA, 10.4 strikeouts per nine innings) will start in Tuesday’s matchup opposite righthander Sandy Alcantara (2-4, 3.46 ERA, 8.9 SO/9). Ray has helped his teams go 11-5 in his last 16 starts at home, although the total has gone OVER in six of his last 10 games in his home park. Ray has a 2.31 ERA and 1.026 WHIP (walks and hits divided by innings) in 39 career innings against the Marlins. Alcantara, who has never faced the Blue Jays, has helped the Marlins go 6-2 over his last eight starts as an away underdog with the total going UNDER four times with one PUSH.

Rookie righthander Alek Manoah (1-0, 0.00 ERA, 10.5 SO/9 in one MLB start) will make his second career start on Wednesday, while righthander Pablo López (1-3, 2.71 ERA, 8.4 SO/9) will start for the Marlins. Manoah used his fastball-slider combination to good effect to pitch six shutout innings in his MLB debut against the New York Yankees on May 27. López, who has not faced the Blue Jays in his career, has helped Miami go 6-5 in his last 11 road starts. The total has gone UNDER in two of his last three starts on the road.

The Blue Jays have an off-day on Thursday before hosting a three-game series against the Houston Astros.